Editor profile: Guest editor of special issue “Bile Acids and Nuclear Receptors in Digestive System and Therapy”

16/j.apsb.2015.03.004 cess under CC BY-NC-ND license. Immunology at the University of Arkansas for Medical Science, in 2001, a Ph.D. degree in Toxicology at theUniversity ofKansasMedical Center, and from 2001 to 2004, the post-doctoral training at the NCI, NIH. Dr. Guo has been a tenured faculty at the Department of Pharmacology, Toxicology and Therapeutics at the University of Kansas Medical Center (2004–2012), and a tenured faculty at the Rutgers University (2012–present). For the last two decades, Dr. Guo has determined the roles of nuclear receptors and signaling pathways that are critical for liver homeostasis and metabolism, including farnesoid X receptor (FXR), pregnane X receptor, constitutive androstane receptor, fibroblast growth factor 15/19 and bile acids. The highlights of Dr. Guo's research findings include understanding the cellular and molecular mechanism by which tissue-specific FXR functions to regulate bile acid homeostasis, transcriptional regulation of drug metabolism and transport, non-alcoholic hepatosteatosis, liver and colon carcinogenesis, and liver regeneration. Dr. Guo has published over 75 peer-reviewed research and review articles on nuclear receptors and their regulation of liver and intestine functions. As the PI or Co-I on several NIH funding, Dr. Guo's laboratory has laid the ground work by determining the role of intestinal FXR in regulating liver functions. Dr. Guo is a member of several scientific societies, scientific reviewer for the US and Italian NIH and private foundations, editorial board member and ad hoc manuscript reviewers for numerous prestigious journals, and invited speakers for national and international lectures and meetings.